Ivermectin for Treatment of COVID-19?

 Ivermectin for Treatment of COVID-19?

 

Hemat Abd El Salam Ahmed Salama (1)

Mohamed Abd El-Rahman Hassan El-Shayeb (2)

Ahmed Nour El-Din Hassan (3,4)

Ghada Essam El-Din Amin (1,5)

Mohamed Farouk Allam (1)

Eman El- Sayed Ahmed (2)

 

1. Department of Family Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

2. Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

3. Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

4. Department of Clinical Pharmacology, Faculty of Medicine, Galala University, Cairo, Egypt.

5. Department of Community Medicine, Faculty of Medicine, 6th of October University, Cairo, Egypt.

 

World Journal of Medical Microbiology, 2022, 1, 474

 

DOI: 10.31586/wjmm.2022.474

 

Abstract:

Many attempts have been made to repurpose existing and approved drugs for the treatment of COVID-19 infection. This involves anti-malarial drugs such as hydroxychloroquine and chloroquine, which have been shown to be less successful than initially believed, with a substantial risk of often fatal complications and interactions. This also involves Remdesivir, which has been shown to decrease recovery time significantly in hospitalized patients. However, for patients who are not yet hospitalized, there is no currently accepted treatment. Treating patients before they need to be admitted or even prophylactically could greatly decrease the load on hospitals, protect healthcare workers and reduce the spread of COVID-19. An in-vitro study indicated that Ivermectin was dynamic against COVID-19-infected cell. Ivermectin has antimicrobial, antiviral, and anticancer, immunomodulatory properties. This drug could reduce the viral load in COVID-9 infected patients, with potential effect on disease progression and spread. Therefore, Ivermectin may be a therapeutic choice for treatment of COVID-19, however, there is still a lack of evidence-based studies to support ivermectin treatment of patients with COVID-19.

 

Keywords: Coronavirus, COVID-19, Ivermectin, Treatment, Review.

 

World Journal of Medical Microbiology, 2022, 1, 474

 

https://www.scipublications.com/journal/index.php/wjmm/article/view/474